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Nicotinic acid (but not nicotinamide) when administered in pharmacological doses of 24 g/day lowers plasma cholesterol levels and has been shown to be a useful therapeutic for hypercholesterolemia

However, stacking both requires a well-planned cycle, as IGF-1 is a potent growth factor that may increase systemic effects like muscle growth and insulin sensitivity

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Figure 1 Subject Selection, Clinical Encounters, and Blood Collection Patients were recruited from the on-campus clinic, the Patient Care Center (PCC) of Western University of Health Sciences, from October 2018 until the target sample size was reached for both the experimental and placebo-controlled arm